Protocolos/Algoritmos/Diretrizes/Fluxogramas

International Consensus on Drug Allergy

Demoly et al.
Allergy 69 (2014) 420–437 © 2014
Número: 2904 / Publicado em 06/03/2015 - 15:46

When drug reactions resembling allergy occur, they are called drug hypersensitivity reactions (DHRs) before showing the evidence of either drug-specific antibodies or T cells. DHRs may be allergic or nonallergic in nature, with drug allergies being immunologically mediated DHRs. These reactions are typically unpredictable. They can be life-threatening, may require or prolong hospitalization, and may necessitate changes in subsequent therapy. Both under diagnosis (due to under-reporting) and over diagnosis (due to an overuse of the term ‘allergy’) are common.

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